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One of the urgent problems of modern obstetrics is the early detection of irregularities in the development of the uteroplacental vessels system in patients with severe disorders in the history. Aim: to evaluate the predictive value of re-development of obstetric pathology on the basis of the uterine artery Doppler on 11–14 weeks of pregnancy. Patients and methods. 410 patients in I trimester of pregnancy were examined with fetal growth restriction, preeclampsia and/or fetal death and/or a history of preterm delivery were. The influence of physical factors and obstetric history on the state of uterine blood flow in the I trimester of pregnancy was studied. Results. The optimal Doppler indexes was calculated; a high predictive ability of the pulsation index in the uterine arteries with respect to pregnancy complications with early clinical manifestation, severe preeclampsia and combined obstetric complications was detected. Conclusions. Our data support the possibility of preclinical diagnosis of obstetrical complications in patients with complicated obstetric history.


About the authors

G. M. Savel'eva

Russian National Research Medical University, Moscow, Russian Federation

Author for correspondence.

RAMS academician, Head of the Department of Obstetrics and Gynecology, Department f Pediatrics, N.I. Pirogov Russian National Research Medical University
Address: 117997, Moscow, street Ostrovityanova, 1; tel.: (495) 718-34-72

Russian Federation

E. Yu. Bugerenko

Center for Family Planning and Reproduction Department of Health in Moscow, Russian Federation


PhD, obstetrician-gynecologist, Center of Family Planning and Reproductive Moscow Health Department
Address: 113209, Moscow, Sevastopol`sky avenue, 24-A; tel.: (499) 794-43-73

Russian Federation

O. B. Panina

Moscow State University, Russian Federation


PhD, Professor, Department of Obstetrics and Gynecology, Faculty of Fundamental Medicine Lomonosov Moscow State University
Address: 119192, Moscow Lomonosov Ave, on 31/5; tel.: (495) 331-91-81

Russian Federation


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