FEATURES OF THE FUNCTIONING OF THE THYROID GLAND IN HIV-INFECTED

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Abstract


In the article the current literature, devoted to the peculiarities of functioning of the thyroid gland in patients with HIV infection, is analyzed. Based on the analysis of literature data bases demonstrated the structure of thyroid function disorders in HIV-infected, as well as the mechanisms of the pathogenesis of these disorders. In the structure of thyroid function is dominated by hypothyroidism, euthyroid pathological syndrome, Graves' disease, for which the opportunistic infections are triggers immune activation.  It should be noted that the step of acquired immunodeficiency syndrome is accompanied by the development of inflammatory and neoplastic processes in the thyroid gland. Convincingly demonstrated the negative impact of highly active antiretroviral therapy in HIV-positive for the development of thyroid dysfunction, in connection which the expediency of forming risk groups and the timely correction of the projected thyroid diseases.

 


About the authors

E. V. Timofeeva

Scientific Center of Family Health and Human Reproduction Siberian Branch of Russian Academy of Medical Sciences, Irkutsk, Russian Federation

Author for correspondence.
Email: eve_gin@list.ru

Russian Federation PG student of the Federal State Budgetary Institution “Scientific Centre of the Family Health and Human Reproduction Problems” under the Siberian Branch of RAMS. Address: 16, Timiryazeva St., Irkutsk, 664003, tel.: (3952) 20-76-36

O. Ya. Leshchenko

Scientific Center of Family Health and Human Reproduction Siberian Branch of Russian Academy of Medical Sciences, Irkutsk, Russian Federation

Email: loyairk@mail.ru

Russian Federation PhD, Head of the socially significant infections laboratory of the Federal State Budgetary Institution “Scientific Centre of the Family Health and Human Reproduction Problems” under the Siberian Branch of RAMS. Address: 16, Timiryazeva St., Irkutsk, 664003, tel.: (3952) 20-76-36

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