COMPARATIVE ANALYSIS OF VASCULARIZATION DEGREE OF HEPATOCELLULAR CARCINOMA AND FOCAL NODULAR HYPERPLASIA OF THE LIVER ACCORDING TO COMPUTED TOMOGRAPHY AND MORPHOLOGICAL STUDIES

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Abstract

A comparative analysis of vascularization degree of hepatocellular carcinoma and focal nodular hyperplasia of the liver according to the multislice computed tomography and histological study of tissue is presented. It was established that computed tomography with bolus contrast enhancement allows to study the characteristics of blood supply of the liver and focal formations. Frequently only the use of this method helps to evaluate specific morphological structure of tumors - hepatocellular carcinoma or focal nodular hyperplasia. As an additional differential diagnostic feature is recommended to increase the density determination of tissue formation in the arterial phase computed tomography study. The maximum of vascularization by computed tomography and immunohistochemistry (with antibodies CD34) are installed in a tissue of highly differentiated hepatocellular carcinoma.

About the authors

U. N. Tumanova

Vishnevsky Institute of Surgery, Russian Ministry of Healthcare,
Moscow, Russian Federation
Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perina-tology, Russian Ministry of Healthcare, Moscow, Russian Federation

Author for correspondence.
Email: u.n.tumanova@gmail.com
clinical physician of the Department of Imaging methods of Diagnosis and Treatment of FSBI “A.V. Vishnevskii Surgery Institute”, junior research scientist of the 2nd Department of Morbid anatomy of FSBI “V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology”. Address: 27, B. Serpukhovskaya Street, Moscow, RF, 117997; tel.: +7 (495) 237-37-64 Russian Federation

G. G. Karmazanovskii

Vishnevsky Institute of Surgery, Russian Ministry of Healthcare,
Moscow, Russian Federation

Email: karmazanovsky@ixv.ru
PhD, professor, Head of the Department of Imaging methods of Diagnosis and Treatment of FSBI “A.V. Vishnevskii Surgery Institute”. Address: 27, B. Serpukhovskaya Street, Moscow, RF, 117997; tel.: +7 (495) 237-37-64 Russian Federation

E. A. Dubova

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perina-tology, Russian Ministry of Healthcare, Moscow, Russian Federation

Email: e_dubova@oparina4.ru
MD, senior research scientist of the 2nd Department of Morbid anatomy of FSBI “V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology”. Address: 4, Akad. Oparin Street, Moscow, RF, 117997; tel.: +7 (495) 438-28-92 Russian Federation

A. I. Shchegolev

Academician V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perina-tology, Russian Ministry of Healthcare, Moscow, Russian Federation

Email: ashegolev@oparina4.ru
PhD, professor, Head of the 2nd Department of Morbid anatomy of FSBI “V.I. Kulakov Research Center for Obstetrics, Gynecology and Perinatology”. Address: 4, Akad. Oparin Street, Moscow, RF, 117997; tel.: +7 (495) 438-28-92 Russian Federation

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